Description

Angiotensin III Antipeptide is a specialized synthetic peptide antagonist designed to selectively inhibit the biological activity of Angiotensin III. This compound is a critical research tool for investigating the renin-angiotensin system (RAS), a key pathway in cardiovascular and renal physiology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on hypertension, heart failure, and metabolic disorder research.

Application

• Biomedical Research: Fundamental studies on the specific roles and signaling pathways of Angiotensin III within the renin-angiotensin system.
• Drug Discovery & Development: Used as a reference standard and pharmacological tool in high-throughput screening (HTS) assays to identify and validate novel therapeutic candidates targeting the AT2 receptor.
• Mechanistic Studies: Elucidating the physiological and pathophysiological effects of Angiotensin III in cardiovascular regulation, fluid balance, and tissue remodeling.
• In Vitro & Ex Vivo Models: Application in cell-based assays and isolated tissue preparations to study receptor binding, antagonism, and downstream cellular responses.
• Academic & Clinical Research: Supporting investigations into diseases such as hypertension, heart failure, renal fibrosis, and stroke.
• Biochemical Reagent: Serves as a specific inhibitory agent in enzymatic and receptor-binding assay kits for research purposes.

Basic Information

Product Name	Angiotensin III Antipeptide
CAS No.	133605-55-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Angiotensin III Inhibitor; Ang III Antagonist; Saralasin analogue; [Sar¹, Ala⁸]-Angiotensin III; AT2 Receptor Antagonist (peptide); RAS Inhibitory Peptide; Angiotensin (3-8) hexapeptide antagonist
EINECS	Contact for details

Quality Control

Our Angiotensin III Antipeptide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, dimethyl sulfoxide (DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.