Description

2-(Bromomethyl)-1-Nitro-3-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block characterized by its reactive bromomethyl and electron-withdrawing nitro and trifluoromethyl substituents. This unique structure makes it an essential intermediate for the synthesis of complex molecules, offering chemists a versatile handle for cross-coupling, nucleophilic substitution, and further functionalization. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylphenyl moiety.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the benzyl bromide functionality allows for further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or functional additives for polymers and advanced organic materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to its reactive bromomethyl group for bioconjugation.
• Custom Synthesis and Contract Manufacturing: A critical building block for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	2-(Bromomethyl)-1-Nitro-3-(Trifluoromethyl)Benzene
CAS No.	133605-26-2
Molecular Formula	C9H5BrF3NO2
Molecular Weight	296.04 g/mol
Synonyms	1-Nitro-2-(bromomethyl)-3-(trifluoromethyl)benzene; 2-Bromomethyl-1-nitro-3-trifluoromethylbenzene; α-Bromo-2-nitro-α,α,α-trifluoro-p-xylene; 3-(Trifluoromethyl)-2-(bromomethyl)nitrobenzene; 2-Nitro-α-(bromomethyl)-α,α,α-trifluoro-p-xylene; (2-Nitro-6-(trifluoromethyl)phenyl)methyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-1-Nitro-3-(Trifluoromethyl)Benzene is produced and analyzed under a strict quality management system. We guarantee high-purity material suitable for demanding synthetic applications, with comprehensive testing including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature of the compound, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.