Description

(2B,3A,5B,7A)-2,3,7-Trihydroxy-Cholan-24-Oic Acid is a high-purity, multi-hydroxylated bile acid derivative. This compound is a critical intermediate and reference standard in advanced pharmaceutical research and development, particularly for metabolic and liver-related studies. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise and reliable bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents targeting metabolic pathways.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: A vital tool for studying bile acid metabolism, liver function, and nuclear receptor (e.g., FXR) signaling in academic and industrial R&D.
• Metabolite Standard: Employed in mass spectrometry and chromatography as a standard for identifying and quantifying related metabolites in biological samples.
• Fine Chemical Synthesis: Acts as a sophisticated chiral starting material for the production of specialized steroids and other complex organic molecules.

Basic Information

Product Name	(2B,3A,5B,7A)-2,3,7-Trihydroxy-Cholan-24-Oic Acid
CAS No.	133565-87-4
Molecular Formula	C24H40O6
Molecular Weight	424.57 g/mol
Synonyms	2α,3β,7α-Trihydroxy-5β-cholan-24-oic Acid; 2,3,7-Trihydroxycholic Acid; 2,3,7-Trihydroxy-5β-cholan-24-oic Acid; 3β,7α-Dihydroxy-5β-cholan-24-oic Acid 2α-ol; Ursodeoxycholic Acid Metabolite; UDCA Metabolite; 2,3,7-THCA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2B,3A,5B,7A)-2,3,7-Trihydroxy-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.