Description

Tyrphostin B56 CAS NO 133550-41-1 is a potent and selective inhibitor of protein tyrosine kinases, specifically targeting the epidermal growth factor receptor (EGFR) pathway. This compound is a critical research tool for elucidating signal transduction mechanisms and studying cellular processes related to growth, proliferation, and differentiation. It is primarily utilized by researchers and scientists in the fields of oncology, biochemistry, and pharmacology for drug discovery and academic research.

Application

• Biochemical Research: A key reagent for studying EGFR-mediated signal transduction pathways and tyrosine kinase activity in vitro.
• Oncology Research: Used to investigate the role of EGFR in cancer cell proliferation and to screen for potential anti-cancer therapeutics.
• Cell Biology Studies: Employed to modulate cellular responses to growth factors and to understand mechanisms of cell cycle regulation.
• Pharmacology & Drug Discovery: Serves as a reference standard and a lead compound in the development of novel tyrosine kinase inhibitors.
• Academic & Institutional Laboratories: Essential for fundamental research in universities and research institutes focusing on molecular biology and cellular signaling.

Basic Information

Product Name	Tyrphostin B56
CAS No.	133550-41-1
Molecular Formula	C16H12N2O3
Molecular Weight	280.28 g/mol
Synonyms	AG 556; Tyrphostin AG 556; (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; RG 14620; B56; EGFR Inhibitor AG 556; 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-, (2E)-
EINECS	Contact for details

Quality Control

Our Tyrphostin B56 is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals to guarantee product integrity and reliable performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.