Description

2-(2-Fluorophenyl)-1,3-Dioxolane is a versatile fluorinated heterocyclic compound that serves as a critical synthetic intermediate and protecting group reagent in advanced organic synthesis. Its unique structure, featuring a fluorinated aromatic ring fused to a 1,3-dioxolane moiety, makes it a valuable building block for constructing complex molecules with tailored properties. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to introduce fluorine atoms or masked carbonyl functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental stability.
• Organic Synthesis Reagent: Acts as a protecting group for aldehydes and ketones in multi-step synthetic routes, offering stability under various reaction conditions.
• Liquid Crystal & OLED Material Research: Fluorinated component used in the development of advanced electronic display materials and organic light-emitting diodes.
• Flavor & Fragrance Chemistry: Intermediate for creating complex aromatic molecules with specific olfactory profiles.
• Polymer Modification: Used to incorporate fluorine into polymer backbones to alter thermal stability, solubility, and surface properties.

Basic Information

Product Name	2-(2-Fluorophenyl)-1,3-Dioxolane
CAS No.	133393-02-9
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	2-(2-Fluorophenyl)-1,3-dioxolane; 2-Fluorobenzaldehyde ethylene acetal; o-Fluorobenzaldehyde ethylene acetal; 1,3-Dioxolane, 2-(2-fluorophenyl)-; 2-(2-Fluorophenyl)-[1,3]dioxolane; Benzaldehyde, 2-fluoro-, cyclic ethylene acetal; (2-Fluorophenyl)-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)-1,3-Dioxolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and industrial applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.20 g/cm³
Refractive Index (n20D)	~1.510 - 1.520

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.