Description

3-Nitro-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its nitro and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs), where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and optimizing synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a vital building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of advanced materials, including liquid crystals, organic semiconductors, and functional polymers.
• Chemical Biology & Proteomics: Employed as a tagging or labeling reagent in biochemical assays and for modifying biomolecules.
• Organic Synthesis & Catalysis: Acts as a versatile substrate for cross-coupling reactions, nucleophilic aromatic substitutions, and other transformations to create complex molecular architectures.
• Fluorine Chemistry Studies: An important compound for investigating the effects of the trifluoromethyl group on reactivity, lipophilicity, and electronic properties in heterocyclic systems.

Basic Information

Product Name	3-Nitro-2-(Trifluoromethyl)Pyridine
CAS No.	133391-63-6
Molecular Formula	C6H3F3N2O2
Molecular Weight	192.10 g/mol
Synonyms	2-(Trifluoromethyl)-3-nitropyridine; 3-Nitro-2-trifluoromethylpyridine; 3-Nitro-2-(trifluoromethyl)pyridine; Pyridine, 3-nitro-2-(trifluoromethyl)-; 2-Trifluoromethyl-3-nitropyridine; 3-Nitro-α,α,α-trifluoro-2-picoline
EINECS	Contact for details

Quality Control

Our 3-Nitro-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP and ISO 9001 principles to meet the stringent requirements of our global B2B clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.