Description

2,3,5-Trifluorotoluene is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique trifluoromethyl-substituted benzene structure, which imparts desirable electronic and steric properties to target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorine motifs for enhanced bioactivity and material performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine atoms improve efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to introduce fluorine into polymer chains, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.
• Research & Development: A valuable tool for medicinal chemistry and material science R&D for exploring structure-activity relationships.

Basic Information

Product Name	2,3,5-Trifluorotoluene
CAS No.	132992-29-1
Molecular Formula	C7H5F3
Molecular Weight	146.11 g/mol
Synonyms	1,2,4-Trifluoro-5-methylbenzene; 2,3,5-Trifluoromethylbenzene; α,α,α-Trifluoro-2,3,5-trimethyltoluene; Toluene, 2,3,5-trifluoro-; 2,3,5-Trifluoro-1-methylbenzene; 3,4,6-Trifluorotoluene
EINECS	Contact for details

Quality Control

Our 2,3,5-Trifluorotoluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and lot-to-lot consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids and strong oxidizers. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.30 g/cm³
Boiling Point	~145-150°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.