Description

Scopoletin B-D-Glucuronide is a specific glucuronide conjugate of the coumarin derivative scopoletin. This compound is of significant interest in biochemical and pharmaceutical research, particularly in the study of drug metabolism and the bioavailability of natural products. It serves as a crucial analytical standard and reference material for scientists and quality control professionals. Key applications include use in metabolite identification, pharmacokinetic studies, and as a biomarker in various research and development pipelines.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and qualification of scopoletin metabolites in drug development and bioanalytical assays.
• Metabolite Research: Essential for studying Phase II drug metabolism pathways, specifically glucuronidation, to understand drug clearance and activity.
• Biomarker Analysis: Employed in clinical and preclinical research as a biomarker for the consumption or metabolism of scopoletin-containing botanicals and pharmaceuticals.
• Analytical Method Development: Serves as a critical standard for developing and validating HPLC, LC-MS, and other chromatographic methods in analytical laboratories.
• Natural Product Chemistry: Used in research focusing on the isolation, characterization, and activity of coumarin derivatives from natural sources.
• Quality Control (QC) & Assurance: Integral for ensuring the accuracy and reliability of test results in pharmaceutical and nutraceutical quality control laboratories.

Basic Information

Item	Detail
Product Name	Scopoletin B-D-Glucuronide
CAS No.	132752-65-9
Molecular Formula	C22H26O13
Molecular Weight	498.44 g/mol
Synonyms	Scopoletin β-D-Glucuronide; Scopoletin Glucuronide; 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one β-D-Glucopyranosiduronic Acid; 7-((β-D-Glucopyranuronosyl)oxy)-6-methoxy-2H-chromen-2-one; 6-Methoxy-7-β-D-glucuronosyloxycoumarin; Scopoletin-7-O-β-D-glucuronide; Coumarin glucuronide derivative
EINECS	Contact for details

Quality Control

Our Scopoletin B-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation, spectroscopic identification (IR, NMR, MS), and residual solvent analysis, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.