Description

3-(Pentafluoroethyl)-1-Phenyl-1H-Pyrazol-5-Ol is a high-value fluorinated pyrazole derivative, a key building block in advanced chemical synthesis. Its unique structure, featuring a pentafluoroethyl group, provides exceptional electronic and steric properties critical for developing novel materials and active compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to incorporate fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity in their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a key fluorinated scaffold for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Used in the research and development of specialty polymers, liquid crystals, and organic electronic materials where fluorine substitution tunes electronic properties.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Life Science Reagents: Employed in the design and synthesis of biochemical probes and fluorinated tags for imaging and diagnostic applications.

Basic Information

Product Name	3-(Pentafluoroethyl)-1-Phenyl-1H-Pyrazol-5-Ol
CAS No.	132631-84-6
Molecular Formula	C11H7F5N2O
Molecular Weight	278.18 g/mol
Synonyms	5-Hydroxy-3-(pentafluoroethyl)-1-phenyl-1H-pyrazole; 1-Phenyl-3-(pentafluoroethyl)-1H-pyrazol-5-ol; 3-(Pentafluoroethyl)-1-phenyl-1H-pyrazol-5-ol; 5-Pyrazolol, 3-(pentafluoroethyl)-1-phenyl-; Pentafluoroethyl phenyl pyrazolol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fluorinated intermediates. Each batch of 3-(Pentafluoroethyl)-1-Phenyl-1H-Pyrazol-5-Ol is analyzed using advanced techniques including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality management system supports cGMP standards for pharmaceutical-grade applications, ensuring traceability and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.