Description

3-Fluoro-4-Iodobenzotrifluoride is a high-value, multi-functional halogenated aromatic building block. This compound matters for its unique molecular architecture, combining fluorine, iodine, and a trifluoromethyl group to enable precise structural modifications in advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine and iodine substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl systems.
• Positron Emission Tomography (PET) Tracer Development: Utilized in radiochemistry for creating fluorine-18 labeled tracers for medical imaging.
• Polymer & Material Science: Acts as a monomer or modifier for introducing fluorinated segments into polymers to alter surface properties, chemical resistance, and thermal stability.

Basic Information

Product Name	3-Fluoro-4-Iodobenzotrifluoride
CAS No.	132554-73-5
Molecular Formula	C7H2F4I
Molecular Weight	303.99 g/mol
Synonyms	1-Fluoro-2-iodo-5-(trifluoromethyl)benzene; 4-Iodo-3-fluorobenzotrifluoride; 3-Fluoro-4-iodo-alpha,alpha,α-trifluorotoluene; 2-Iodo-1-fluoro-4-(trifluoromethyl)benzene; 3-Fluoro-4-iodobenzotrifluoride; 3-Fluoro-4-iodo-1-(trifluoromethyl)benzene; Benzene, 1-fluoro-2-iodo-5-(trifluoromethyl)-; 132554-73-5
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Iodobenzotrifluoride is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.