Description

5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-2-Naphthalenesulfonyl Chloride is a specialized organic intermediate featuring a sterically hindered tetralin backbone with a reactive sulfonyl chloride group. This compound matters for its role as a key building block in the synthesis of complex molecules, offering a unique combination of lipophilicity and structural rigidity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where its bulky structure can enhance biological activity and environmental stability.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce sulfonamide or sulfonate groups into specialty polymers, improving their thermal or chemical resistance.
• Dye and Pigment Manufacturing: Employed in the production of high-performance, light-fast colorants and imaging materials.
• Ligand and Catalyst Development: Utilized to create sophisticated chiral ligands or organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a building block for organic electronic materials, such as those used in OLEDs or semiconductors.

Basic Information

Product Name	5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-2-Naphthalenesulfonyl Chloride
CAS No.	132392-26-8
Molecular Formula	C14H19ClO2S
Molecular Weight	286.82 g/mol
Synonyms	5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-sulfonyl chloride; 2-Naphthalenesulfonyl chloride, 5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-; Tetramethyltetrahydronaphthalenesulfonyl chloride; TMTHN-2-Sulfonyl Chloride; 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-2-naphthylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-2-Naphthalenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.