Description

R-(+)-Etomoxir Carboxylate, Potassium Salt is a high-purity, enantiomerically pure potassium salt derivative of the well-known compound etomoxir. This product is a critical research-grade biochemical tool used to selectively inhibit carnitine palmitoyltransferase I (CPT1), a key enzyme in mitochondrial fatty acid oxidation. It is essential for researchers and developers in the life sciences, particularly those investigating metabolic disorders, cardiac energetics, and cancer cell metabolism. The compound is supplied as a hygroscopic solid, requiring careful handling and storage to maintain its integrity and activity.

Application

• Metabolic Research: A primary tool for studying fatty acid oxidation pathways and energy metabolism in cells and tissues.
• Cardiology Research: Used to investigate the role of fatty acid metabolism in heart function, ischemia, and heart failure models.
• Oncology Research: Applied in cancer metabolism studies to explore the dependency of certain tumors on fatty acid oxidation for growth and survival.
• Pharmacology & Drug Discovery: Serves as a reference standard and a biochemical probe in screening assays for novel metabolic modulators.
• Biochemical Assay Development: Utilized as a key inhibitor in enzymatic assays to measure CPT1 activity and validate assay systems.
• Academic & Institutional Research: Fundamental for university and research institute labs focused on biochemistry, physiology, and molecular biology.

Basic Information

Product Name	R-(+)-Etomoxir Carboxylate, Potassium Salt
CAS No.	132308-39-5
Molecular Formula	C15H18KO4
Molecular Weight	301.40 g/mol
Synonyms	(R)-(+)-Etomoxir Potassium Salt; (R)-Etomoxir Potassium Salt; Potassium (R)-2-[4-(2-Chloro-3-trifluoromethylbenzyloxy)phenyl]-2-hydroxyacetate; (R)-Etomoxir; (R)-Etomoxir Carboxylic Acid Potassium Salt; CPT1 Inhibitor (R)-enantiomer; (R)-Etomoxir Carboxylate K Salt
EINECS	Contact for details

Quality Control

Our R-(+)-Etomoxir Carboxylate, Potassium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity suitable for research applications. Each lot is thoroughly characterized and tested. A comprehensive Certificate of Analysis (COA) is provided, detailing purity, identity, and chiral purity. We support research compliance and traceability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (R-enantiomer)
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.