Description

2,2-Dimethyl-6-Chromanesulfonyl Chloride is a specialized organic sulfonyl chloride derivative, serving as a critical building block in advanced chemical synthesis. Its core value lies in its high reactivity as a sulfonylation agent, enabling the introduction of the sulfonyl functional group into target molecules with precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting specific enzyme inhibition.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators requiring sulfonamide or sulfonate functionalities.
• Material Science Research: Employed in the creation of specialized polymers, dyes, and functional materials where the chromane scaffold imparts unique optical or stability properties.
• Chemical Biology Probes: Acts as a reactive handle for labeling or modifying biomolecules in proteomics and biochemical assay development.
• Fine Chemical Production: Intermediate for manufacturing complex, high-value specialty chemicals used in various industrial and research applications.

Basic Information

Product Name	2,2-Dimethyl-6-Chromanesulfonyl Chloride
CAS No.	131880-55-2
Molecular Formula	C11H13ClO3S
Molecular Weight	260.74 g/mol
Synonyms	6-Chlorosulfonyl-2,2-dimethylchromane; 2,2-Dimethylchroman-6-sulfonyl chloride; 2,2-Dimethyl-2H-chromene-6-sulfonyl chloride; 2,2-Dimethyl-6-sulfonylchlorochromane; Chromane-6-sulfonyl chloride, 2,2-dimethyl-; 131880-55-2; 2,2-Dimethylchroman-6-sulfonchlorid
EINECS	Contact for details

Quality Control

Every batch of 2,2-Dimethyl-6-Chromanesulfonyl Chloride is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.