Description

D-[2-13C]Threo-Pent-2-Ulose is a stable isotope-labeled carbohydrate derivative, specifically a 13C-labeled ketopentose. This compound is critical for advanced research requiring precise metabolic pathway tracing and structural elucidation in complex biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications in nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and metabolic flux analysis.

Application

• Metabolic Pathway Tracing: Serves as a crucial tracer in 13C-based metabolic flux analysis (MFA) to map and quantify intracellular metabolic networks in microbial, plant, and mammalian systems.
• NMR Spectroscopy: Used as an internal standard or labeled substrate in Nuclear Magnetic Resonance (NMR) studies for the structural characterization of complex carbohydrates and metabolic intermediates.
• Mass Spectrometry (MS): Enhances detection sensitivity and specificity in LC-MS and GC-MS platforms for quantitative analysis of pentose phosphate pathway intermediates and related metabolites.
• Pharmaceutical R&D: Employed in drug discovery and development for studying drug metabolism, pharmacokinetics (DMPK), and the mechanism of action of therapeutics targeting carbohydrate metabolism.
• Biochemical Research: A key reagent for investigating enzyme kinetics, carbohydrate chemistry, and the biosynthesis of nucleotides and cofactors.
• Diagnostic Agent Development: Potential use in the formulation of advanced diagnostic probes and imaging agents for medical research.

Basic Information

Product Name	D-[2-13C]Threo-Pent-2-Ulose
CAS No.	131771-47-6
Molecular Formula	C5H10O5 (with 13C at position 2)
Molecular Weight	~151.12 g/mol (13C labeled)
Synonyms	(2-13C)-D-Threo-pent-2-ulose; D-[2-13C]Threo-2-Pentulose; 13C Labeled D-Threo-Pentulose; 1,3,4,5-Tetrahydroxy-2-[13C]pentan-2-one; [2-13C]-D-Threo-Pentulose; Isotopically Labeled Ketopentose; 13C-Labeled Carbohydrate Tracer
EINECS	Contact for details

Quality Control

Our D-[2-13C]Threo-Pent-2-Ulose is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and MS to confirm identity, isotopic enrichment (typically >99 atom % 13C), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with rigorous internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.