Description

(2-Trifluoromethyl-Pyridin-3-Yl)-Methanol is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its core value lies in the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and manufacture of advanced herbicides, fungicides, and insecticides, where the CF3 group improves biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals that require fluorinated aromatic components for specific electronic or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	(2-Trifluoromethyl-Pyridin-3-Yl)-Methanol
CAS No.	131747-57-4
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	3-(Hydroxymethyl)-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-3-pyridinemethanol; (2-Trifluoromethyl-3-pyridinyl)methanol; 3-Pyridinemethanol, 2-(trifluoromethyl)-; α-(Trifluoromethyl)-3-pyridinemethanol
EINECS	Contact for details

Quality Control

Our (2-Trifluoromethyl-Pyridin-3-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.