Description

Diazonamide A CAS NO 131727-01-0 is a complex, marine-derived macrocyclic peptide known for its potent and unique biological activity. This compound is of significant interest in advanced pharmaceutical research due to its powerful anti-mitotic properties, which disrupt microtubule dynamics. It serves as a critical reference standard and a promising lead compound for researchers in oncology and chemical biology, particularly those investigating novel mechanisms for cancer therapy and cellular process modulation.

Application

• Pharmaceutical Research & Development: As a high-purity reference standard for analytical method development, validation, and quality control in drug discovery pipelines.
• Oncology Research: Investigation as a lead compound for the development of novel anti-cancer therapeutics targeting microtubule assembly and mitosis.
• Chemical Biology Studies: Used as a molecular probe to study cell division, cytoskeleton function, and mechanisms of apoptosis.
• Academic & Institutional Research: Serves as a key reagent in university and institutional labs for fundamental studies in marine natural products and medicinal chemistry.
• Biochemical Assay Development: Utilized in high-throughput screening (HTS) campaigns and the development of cell-based assays to identify compounds with similar mechanisms of action.

Basic Information

Product Name	Diazonamide A
CAS No.	131727-01-0
Molecular Formula	C40H34Cl2N8O8
Molecular Weight	825.66 g/mol
Synonyms	Diazonamide A; Diazonamide; Diazonamide A (from Diazona angulata); Diazonamide A, Diazona angulata metabolite; 131727-01-0; UNII-1Z9K9N1569; 1Z9K9N1569; CHEMBL1237105; BDBM50388835; SCHEMBL15520; AKOS015915506; AS-10235; ZINC000003869726; CCG-269022; HY-12597; NSC-76027; AOB33897; SR-01000866120; SR-01000866120-1; HMS3261G22; ZINC000003869726.
EINECS	Contact for details

Quality Control

Our Diazonamide A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity confirmation and structural verification via spectroscopic methods. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment, supporting compliance with rigorous research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.