Description

Geranylgeranylcysteine is a specialized, high-purity biochemical compound, also known by its CAS number 131404-69-8. This molecule is a critical intermediate in the biosynthesis of proteins involved in cellular signaling and membrane anchoring processes. It is essential for researchers and manufacturers in the pharmaceutical and life science sectors developing novel therapeutics and conducting advanced biochemical studies. Its precise structure makes it a valuable tool for probing protein prenylation pathways and related biological functions.

Application

• Pharmaceutical Research & Development: A key intermediate and reference standard in the study of protein prenylation, particularly for geranylgeranylated proteins like Rho and Rac GTPases.
• Biochemical Pathway Analysis: Used as a substrate or inhibitor in enzymatic assays to investigate the function of protein geranylgeranyltransferase I (GGTase-I).
• Drug Discovery: Serves as a building block or a lead compound in the development of novel therapeutics targeting cancers, cardiovascular diseases, and neurodegenerative disorders linked to aberrant prenylation.
• Academic Research: Employed in university and institutional labs for fundamental studies on cell signaling, cytoskeletal organization, and membrane trafficking.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized kits and reagents for detecting prenylation-related enzymatic activity.
• Cosmeceutical R&D: Investigated for its role in cellular processes relevant to skin health and aging, supporting advanced cosmetic ingredient development.

Basic Information

Product Name	Geranylgeranylcysteine
CAS No.	131404-69-8
Molecular Formula	C23H39NO2S
Molecular Weight	393.63 g/mol
Synonyms	Geranylgeranyl-L-cysteine; (2R)-2-Amino-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]sulfanylpropanoic acid; L-Cysteine, S-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl)-; Farnesylcysteine analog; Protein prenylation intermediate; GGC; S-Geranylgeranylcysteine
EINECS	Contact for details

Quality Control

Our Geranylgeranylcysteine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.