Description

Efrapeptin F CAS NO 131353-66-7 is a potent, naturally occurring peptide antibiotic belonging to the efrapeptin family, a group of mitochondrial ATPase inhibitors. This compound is valued for its specific biological activity, making it a critical tool in biochemical and pharmacological research. It is primarily sought after by researchers and manufacturers in the life sciences sector for applications in enzymology, mitochondrial function studies, and as a lead compound in antimicrobial and anticancer agent development.

Application

• Biochemical Research: Used as a specific inhibitor of mitochondrial F1F0-ATPase (ATP synthase) to study cellular energy metabolism, oxidative phosphorylation, and mitochondrial function.
• Pharmacological Studies: Serves as a reference standard and investigative tool in the development of novel antimicrobial and antifungal agents due to its potent bioactivity.
• Anticancer Research: Investigated for its potential to induce apoptosis in cancer cells by disrupting mitochondrial membrane potential and ATP production.
• Insecticidal & Acaricidal Agent: Explored in agricultural research for its natural pesticidal properties against mites and insects.
• Enzyme Inhibition Assays: Employed in high-throughput screening and in vitro assays to identify and characterize other ATPase inhibitors or modulators.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related peptide mixtures or natural product extracts.

Basic Information

Product Name	Efrapeptin F
CAS No.	131353-66-7
Molecular Formula	C~58-60~H~95-99~N~15-17~O~12-14~
Molecular Weight	~1200 - 1400 g/mol
Synonyms	Efrapeptin F; Antibiotic A23871F; Leu-Aib-Iva-Aib-Aib-Leu-Bta-Aib-Gly-Aib-Aib-Aib-Pro; ATPase inhibitor, efrapeptin type F; Mitochondrial F1F0-ATPase inhibitor F; Aib-rich peptide antibiotic F
EINECS	Contact for details

Quality Control

Our Efrapeptin F is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Potency (ATPase Inhibition)	≥ 90% of reference activity
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.