Description

1H-Indazole-6-Sulfonyl Chloride (Wxc09037) is a high-purity sulfonyl chloride derivative, a crucial building block in modern organic synthesis. This compound serves as a key electrophilic reagent for the introduction of the indazole-6-sulfonyl moiety, enabling the creation of complex molecules with targeted functionalities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the indazole scaffold's bioactivity.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of activity-based probes (ABPs) to study enzyme function.
• Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials requiring sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions for client projects.

Basic Information

Product Name	1H-Indazole-6-Sulfonyl Chloride (Wxc09037)
CAS No.	131290-01-2
Molecular Formula	C7H5ClN2O2S
Molecular Weight	216.64 g/mol
Synonyms	1H-Indazole-6-sulfonyl chloride; 6-Indazolesulfonyl chloride; Indazole-6-sulfonyl chloride; 1H-Indazole-6-sulfonchlorid; 131290-01-2; Wxc09037; 6-(Chlorosulfonyl)-1H-indazole; 1H-Indazol-6-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1H-Indazole-6-Sulfonyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.