Description

n-Nitrosomethyl(1-Methylbutyl)Amine is a specialized nitrosamine compound of significant interest in advanced chemical research and development. This compound serves as a critical intermediate and reference standard for analytical and synthetic chemistry applications. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and chemical manufacturing sectors for method development, impurity profiling, and toxicological studies.

Application

• Pharmaceutical Impurity Analysis: Used as a certified reference material (CRM) for the identification and quantification of nitrosamine impurities in active pharmaceutical ingredients (APIs) and drug products, ensuring compliance with stringent regulatory limits (e.g., EMA, FDA).
• Analytical Method Development: Serves as a key standard for developing and validating sensitive analytical methods, such as LC-MS/MS and GC-MS, for trace-level detection of genotoxic impurities.
• Toxicological Research: Employed in metabolic and carcinogenicity studies to understand the biological impact and risk assessment of nitrosamine compounds.
• Chemical Synthesis Intermediate: Acts as a building block or precursor in the synthesis of more complex molecules for research purposes in organic and medicinal chemistry.
• Quality Control & Assurance: Essential for calibrating equipment and running control samples in quality control laboratories to monitor and control nitrosamine levels in chemical processes.

Basic Information

Product Name	n-Nitrosomethyl(1-Methylbutyl)Amine
CAS No.	130985-76-1
Molecular Formula	C7H16N2O
Molecular Weight	144.22 g/mol
Synonyms	N-Nitroso-N-methyl-1-methylbutylamine; N-Methyl-N-nitroso-1-methylbutylamine; 1-Methylbutyl(methyl)nitrosamine; N-Nitroso-N-methylpentan-2-amine; NMBA (context-specific); Methyl(1-methylbutyl)nitrosamine
EINECS	Contact for details

Quality Control

Every batch of n-Nitrosomethyl(1-Methylbutyl)Amine is manufactured and handled under strict quality management protocols. We provide comprehensive analytical data to support its use as a high-purity reference standard. Our products undergo rigorous quality testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, all handling and storage should minimize exposure to light.

Specification

Item	Specification
Appearance	Clear to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.