Description

(4-Pyridylmethyl)Sulfonyl Chloride Triflate is a specialized organosulfur reagent featuring a reactive sulfonyl chloride group activated by a triflate moiety. This compound matters as a highly versatile building block for introducing the 4-pyridylmethylsulfonyl functional group into target molecules, enabling the synthesis of complex sulfonamides and sulfonate esters. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of sulfonamide-based drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used to create novel sulfonyl-containing herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe Development: Serves as a coupling agent for labeling proteins or other biomolecules with pyridine-based tags for study.
• Material Science Research: Employed in the preparation of functional monomers or ligands for metal-organic frameworks (MOFs) and polymers.
• Cross-Coupling & Functionalization: Acts as an electrophile in palladium-catalyzed cross-coupling reactions or for the functionalization of heterocycles.

Basic Information

Product Name	(4-Pyridylmethyl)Sulfonyl Chloride Triflate
CAS No.	130820-89-2
Molecular Formula	C7H6ClF3NO5S2
Molecular Weight	349.70 g/mol
Synonyms	4-(Chlorosulfonylmethyl)pyridine Trifluoromethanesulfonate; 4-Pyridinemethanesulfonyl Chloride Triflate; 4-(Chlorosulfonylmethyl)pyridinium Triflate; (4-Pyridyl)methanesulfonyl Chloride Trifluoromethanesulfonate; Pyridine-4-methanesulfonyl Chloride Triflate; 4-Pyridylmethylsulfonyl Chloride Trifluoromethanesulfonate; (4-Pyridinylmethyl)sulfonyl Chloride Triflate
EINECS	Contact for details

Quality Control

Our (4-Pyridylmethyl)Sulfonyl Chloride Triflate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.