Description

4-Pyridinemethanesulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group to create novel chemical entities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with sulfonyl functional groups.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Material Science: Employed in the synthesis of functional polymers and advanced materials with specific surface properties.
• Custom Synthesis & Contract Manufacturing: A crucial reagent for custom synthesis houses producing specialized fine chemicals for clients.
• Academic & R&D Laboratories: Used in methodological development and the discovery of new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-Pyridinemethanesulfonyl Chloride
CAS No.	130820-88-1
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	4-Pyridylmethanesulfonyl chloride; (Pyridin-4-yl)methanesulfonyl chloride; 4-Pyridinemethanesulfonyl chloride; 4-Pyridylmethylsulfonyl chloride; p-Pyridinemethanesulfonyl chloride; 4-Pyridylmethanesulphonyl chloride; (4-Pyridinyl)methanesulfonyl chloride; 4-PyCH2SO2Cl
EINECS	Contact for details

Quality Control

Our 4-Pyridinemethanesulfonyl Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.