Description

3,4-Diiodobenzotrifluoride is a versatile fluorinated aromatic building block characterized by its two iodine substituents, which serve as excellent handles for further functionalization via cross-coupling reactions. This compound is essential for the synthesis of complex molecules in advanced research and industrial applications, offering a unique combination of reactivity and stability. It is primarily sought after by pharmaceutical researchers, agrochemical developers, and material scientists for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its structure influences electronic properties and device performance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to construct biaryl and conjugated systems.
• Polymer Chemistry: Incorporated into specialty polymers to impart unique characteristics such as chemical resistance, thermal stability, and specific optical properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3,4-Diiodobenzotrifluoride
CAS No.	130656-70-1
Molecular Formula	C7H3F3I2
Molecular Weight	407.90 g/mol
Synonyms	1,2-Diiodo-4-(trifluoromethyl)benzene; 3,4-Diiodo-α,α,α-trifluorotoluene; 3,4-Diiodobenzotrifluoride; 4-(Trifluoromethyl)-1,2-diiodobenzene; 3,4-Diiodo-α,α,α-trifluoromethylbenzene; Benzene, 1,2-diiodo-4-(trifluoromethyl)-; 3,4-Diiodo-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 3,4-Diiodobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.