Description

n-Methylmesoporphyrin Ix is a chemically modified porphyrin derivative, specifically a methylated form of mesoporphyrin IX. This compound is valued for its role as a potent and selective inhibitor of the enzyme ferrochelatase, which is critical in the heme biosynthesis pathway. It serves as an essential biochemical tool for researchers in life sciences, particularly in studies related to porphyria, heme metabolism, and cellular iron regulation. The product is supplied to meet the stringent requirements of pharmaceutical R&D and advanced biochemical analysis.

Application

• Biochemical Research: Used as a specific inhibitor of ferrochelatase to study heme biosynthesis and related disorders.
• Pharmaceutical Development: Employed in target validation and mechanistic studies for therapies targeting porphyrias and iron metabolism diseases.
• Enzyme Inhibition Studies: Acts as a reference standard in assays to evaluate ferrochelatase activity and screen for potential modulators.
• Cell Biology: Utilized to induce protoporphyrin IX accumulation in cell culture models, facilitating photodynamic therapy research.
• Diagnostic Reagent Development: A key component in developing in vitro diagnostic tests for enzymatic deficiencies.
• Academic Research: Supports fundamental research in biochemistry, molecular biology, and metabolic pathways.

Basic Information

Product Name	n-Methylmesoporphyrin Ix
CAS No.	130641-26-8
Molecular Formula	C₃₅H₃₈N₄O₄
Molecular Weight	578.70 g/mol
Synonyms	N-Methylmesoporphyrin IX; Methylmesoporphyrin; NMMP; N-Methyl mesoporphyrin; Mesoporphyrin IX methyl ester; Ferrochelatase inhibitor N-methylmesoporphyrin; 3,8,13,17-Tetramethyl-21H,23H-porphine-2,18-dipropanoic acid, 7,12-diethyl-1,22-dihydro-22-methyl-, dimethyl ester; 130641-26-8
EINECS	Contact for details

Quality Control

Our n-Methylmesoporphyrin Ix is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all quality parameters. Our quality management system supports compliance with relevant standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Dark purple to brown solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.