Description

Skf 96365 Hydrochloride is a potent and selective inhibitor of store-operated calcium entry (SOCE) and receptor-operated calcium entry (ROCE). This compound is a critical research tool for investigating calcium signaling pathways and their role in various physiological and pathological processes. It is primarily utilized by researchers and scientists in the fields of pharmacology, cell biology, and neuroscience for in vitro and in vivo studies.

Application

• Pharmacological Research: A key tool for studying the mechanisms of calcium influx through store-operated and receptor-operated channels.
• Cell Signaling Studies: Used to elucidate the role of calcium signaling in cellular functions such as proliferation, migration, and gene expression.
• Neuroscience Research: Investigates the involvement of calcium channels in neuronal activity, synaptic transmission, and neurodegenerative disease models.
• Immunology Research: Applied to study calcium-dependent processes in immune cell activation and cytokine production.
• Cardiovascular Research: Used in models exploring calcium handling in cardiac and vascular smooth muscle cells.
• Biochemical Assay Development: Serves as a reference standard and control compound in high-throughput screening and assay validation.

Basic Information

Product Name	Skf 96365 Hydrochloride
CAS No.	130495-35-1
Molecular Formula	C24H26ClN3O3 • HCl
Molecular Weight	476.85 g/mol
Synonyms	SKF-96365 hydrochloride; 1-[β-[3-(4-Methoxyphenyl)propoxy]-4-methoxyphenethyl]-1H-imidazole hydrochloride; SKF 96365; SOCE inhibitor SKF-96365; 1H-Imidazole, 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Skf 96365 Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.