Description

(2S,3R)-n-Hydroxy-N'-[(2S)-1-Methylamino-1-Oxo-3-Phenylpropan-2-Yl]-3-(2-Methylpropyl)-2-(Thiophen-2-Ylsulfanylmethyl)Butanediamide Sodium Salt is a high-purity, complex organic sodium salt with a defined stereochemistry, making it a critical building block for advanced pharmaceutical research and development. This compound matters because it serves as a sophisticated intermediate or active pharmaceutical ingredient (API) precursor, enabling the synthesis of targeted therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on novel drug candidates, particularly in areas requiring precise molecular control.

Application

• Pharmaceutical Intermediate: Key synthetic building block for the development of novel protease inhibitors or other enzyme-targeted therapeutics.
• Biochemical Research: Used as a reference standard or a substrate analog in enzymatic studies and mechanism-of-action investigations.
• Preclinical Development: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology studies during drug discovery.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of complex active pharmaceutical ingredients (APIs).
• Peptidomimetic Synthesis: Acts as a sophisticated component in the design and synthesis of peptide-like molecules with enhanced stability and bioavailability.

Basic Information

Product Name	(2S,3R)-n-Hydroxy-N'-[(2S)-1-Methylamino-1-Oxo-3-Phenylpropan-2-Yl]-3-(2-Methylpropyl)-2-(Thiophen-2-Ylsulfanylmethyl)Butanediamide Sodium Salt
CAS No.	130464-84-5
Molecular Formula	C24H32N3NaO5S2
Molecular Weight	525.64 g/mol
Synonyms	N-Hydroxy-N'-[(1S)-2-(Methylamino)-2-oxo-1-phenylethyl]-3-(2-methylpropyl)-2-[(2-thienylthio)methyl]butanediamide Sodium Salt; L-731,988 Sodium Salt; (2S,3R)-2-[(2-Thienylthio)methyl]-3-isobutyl-N-hydroxy-N'-[(1S)-2-(methylamino)-2-oxo-1-phenylethyl]succinamide Sodium Salt; MK-0507 Sodium Salt; Tryptase Inhibitor I Sodium Salt; L 731988 Sodium Salt; Succinamide Derivative L-731,988 Sodium Salt
EINECS	Contact for details

Quality Control

Our (2S,3R)-n-Hydroxy-N'-[(2S)-1-Methylamino-1-Oxo-3-Phenylpropan-2-Yl]-3-(2-Methylpropyl)-2-(Thiophen-2-Ylsulfanylmethyl)Butanediamide Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for stereochemical purity, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.