Description

Ethanone, 2,2,2-Trifluoro-1-(1H-Pyrrol-3-Yl)- (9Ci) is a high-purity trifluoromethyl ketone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the trifluoroacetyl group and the pyrrole heterocycle, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Chemical Biology & Proteomics: Employed as a reactive handle or affinity probe in the study of enzyme mechanisms and protein labeling.
• Catalyst & Ligand Development: Utilized in the design and synthesis of novel organocatalysts and metal-chelating ligands for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(1H-Pyrrol-3-Yl)- (9Ci)
CAS No.	130408-89-8
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	1-(1H-Pyrrol-3-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1H-pyrrol-3-yl)ethanone; 3-Trifluoroacetylpyrrole; 3-(Trifluoroacetyl)-1H-pyrrole; 1H-Pyrrole-3-carboxaldehyde, trifluoro-; Trifluoroacetyl pyrrole; 3-(2,2,2-Trifluoroacetyl)-1H-pyrrole
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(1H-Pyrrol-3-Yl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.