Description

11-Methoxime Prostaglandin D2 is a chemically modified analog of Prostaglandin D2, designed for enhanced stability and specific biological activity. This compound is a critical intermediate and research tool for investigating the role of prostaglandin pathways in physiological and pathological processes. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions focused on inflammation, allergy, and oncology research.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel therapeutic agents targeting DP and CRTH2 receptors.
• Biochemical Assay Standard: Used as a reference standard in analytical methods (HPLC, LC-MS) for quantifying prostaglandin metabolites in biological samples.
• Mechanistic Studies: A vital tool for studying the signaling pathways, metabolism, and physiological effects of Prostaglandin D2 and its derivatives.
• Inflammation & Allergy Research: Employed in *in vitro* and *in vivo* models to investigate its role in allergic responses, asthma, and other inflammatory conditions.
• Oncology Research: Investigated for its potential effects on tumor progression, angiogenesis, and the tumor microenvironment.
• Process Chemistry: Used as a building block in the scaled-up synthesis of more complex prostaglandin-based molecules under controlled conditions.

Basic Information

Product Name	11-Methoxime Prostaglandin D2
CAS No.	130377-58-1
Molecular Formula	C22H36N2O6
Molecular Weight	424.53 g/mol
Synonyms	11-Methoxime PGD2; 11-(Methoxyimino)-9,15-dihydroxyprosta-5,13-dien-1-oic acid; 9α,15α-Dihydroxy-11-methoxyiminoprosta-5,13-dien-1-oic Acid; PGD2 11-Methoxime; 11-OMe PGD2; Prostaglandin D2 11-Methoxime; 11-Methoxime Prostaglandin D2 Methyl Ester (related ester form)
EINECS	Contact for details

Quality Control

Our 11-Methoxime Prostaglandin D2 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep the primary container sealed within a secondary protective barrier.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.