Description

n-(Phenylethylphosphonyl)-Glycyl-Prolyl-Aminohexanoic Acid is a specialized synthetic peptide derivative containing a unique phosphonyl group. This compound is significant as a key intermediate or building block in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for applications such as protease inhibitor design and novel drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Protease Inhibitor Research: Used in the development and study of inhibitors targeting specific enzymes like dipeptidyl peptidase IV (DPP-IV) and other serine proteases.
• Chemical Biology Tool: Employed as a probe or substrate in enzymatic assays to study enzyme kinetics and mechanisms of action.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Bioconjugation: The reactive functional groups can be utilized for linking to other molecules, carriers, or solid supports.
• Academic Research: Used in university and institutional labs for fundamental research in peptide chemistry and biochemistry.

Basic Information

Product Name	n-(Phenylethylphosphonyl)-Glycyl-Prolyl-Aminohexanoic Acid
CAS No.	130365-59-2
Molecular Formula	C23H36N3O7P
Molecular Weight	497.52 g/mol
Synonyms	N-[(2-Phenylethoxy)phosphinyl]glycyl-L-prolyl-6-aminohexanoic Acid; (Phenylethylphosphonyl)Gly-Pro-Ahx-OH; Gly-Pro-Ahx-Phenylethylphosphonate; GPI 130365-59-2; DPP-IV Inhibitor Intermediate; Peptidomimetic Phosphonate; 6-Aminohexanoic Acid, N-[N-[N-[(2-phenylethoxy)phosphinyl]glycyl]-L-prolyl]-; Ahx-Gly-Pro-Phenylethylphosphonate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity requirements for research and development use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Production can be aligned with cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.