Description

Batroxostatin CAS NO 130357-67-4 is a high-purity synthetic peptide compound, recognized for its potent and selective activity as a snake venom-derived disintegrin. This compound is valued for its critical role in biochemical research, specifically in the study of platelet aggregation and integrin-mediated cellular processes. It is an essential reagent for pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on cardiovascular disease, thrombosis, and cancer metastasis.

Application

• Biochemical Research: Used as a selective inhibitor of integrin αIIbβ3 (GPIIb/IIIa) to study platelet aggregation and thrombus formation mechanisms.
• Pharmaceutical Development: Serves as a reference standard and lead compound in the discovery and development of novel anti-thrombotic and anti-metastatic agents.
• Cell Biology Studies: Employed to investigate cell adhesion, migration, and signaling pathways in various cell types, including cancer and endothelial cells.
• In Vitro Diagnostics (IVD): Utilized as a critical component in assay development for monitoring platelet function and hemostasis.
• Academic & Preclinical Research: A key tool for in vitro and in vivo models to explore the pathophysiology of cardiovascular diseases and metastasis.

Basic Information

Product Name	Batroxostatin
CAS No.	130357-67-4
Molecular Formula	C184H282N52O55S8
Molecular Weight	4114.9 g/mol
Synonyms	Batroxostatin; Disintegrin, Batroxostatin; GPIIb-IIIa Inhibitor (Batroxostatin); Platelet Aggregation Inhibitor Peptide; Arg-Gly-Asp (RGD)-containing Disintegrin; EC 3.4.24.-; Batroxostatin (recombinant); BATO
EINECS	Contact for details

Quality Control

Our Batroxostatin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and endotoxin levels are provided to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider keeping the product under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Endotoxin Level	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.