Description

16-Phenoxy Tetranor Prostaglandin F2α Isopropyl Ester is a synthetic prostaglandin analog, a key intermediate in the development of advanced pharmaceutical compounds. This high-purity intermediate is critical for researchers and manufacturers requiring precise chemical building blocks for drug discovery and synthesis. It is primarily utilized in the development of ophthalmic solutions and other therapeutic agents targeting prostaglandin receptors.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Development: Used in research and production of medications for glaucoma and ocular hypertension.
• Biochemical Research: Serves as a reference standard and probe in prostaglandin receptor studies and signal transduction pathway analysis.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of specialty pharmaceuticals.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and pharmacology projects.

Basic Information

Product Name	16-Phenoxy Tetranor Prostaglandin F2α Isopropyl Ester
CAS No.	130209-78-8
Molecular Formula	C25H36O5
Molecular Weight	416.55 g/mol
Synonyms	16-Phenoxy Tetranor PGF2α Isopropyl Ester; 16-Phenoxy-17,18,19,20-tetranorprostaglandin F2α Isopropyl Ester; Travoprost Impurity; Travoprost Related Compound; 9,11,15-Trihydroxy-16-phenoxy-17,18,19,20-tetranorprost-5-en-1-oic Acid Isopropyl Ester; PF-04475213; AL-6221
EINECS	Contact for details

Quality Control

Our 16-Phenoxy Tetranor Prostaglandin F2α Isopropyl Ester is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.