Description

15-Keto-17-Phenyl-18,19,20-Trinorprostaglandin F2 α-1-Isopropyl Ester is a synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound matters for its role in the synthesis of novel therapeutic agents targeting specific inflammatory and physiological pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing next-generation ophthalmic, cardiovascular, and dermatological treatments.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Research: Used in the development of new glaucoma and ocular hypertension treatments, such as prostaglandin analogs.
• Biochemical Research: Serves as a reference standard and a tool compound for studying prostaglandin receptors (e.g., FP receptors) and their signaling pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value, complex organic molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	15-Keto-17-Phenyl-18,19,20-Trinorprostaglandin F2 α-1-Isopropyl Ester
CAS No.	130209-77-7
Molecular Formula	C29H40O5
Molecular Weight	468.63 g/mol
Synonyms	15-Keto-17-phenyl-18,19,20-trinor-PGF2α isopropyl ester; 17-Phenyl-18,19,20-trinorprostaglandin F2α 15-ketone 1-isopropyl ester; Travoprost Impurity; Travoprost Related Compound; PFG-007; UNII-9K8F8P8X5K; 9K8F8P8X5K; (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3-(3-Phenylpropanoyloxy)-1-propenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Isopropyl Ester
EINECS	Contact for details

Quality Control

Our 15-Keto-17-Phenyl-18,19,20-Trinorprostaglandin F2 α-1-Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.