Description

n-((4-((((4-Chlorophenyl)Sulfonyl)Amino)Carbonyl)Phenyl)Oxomethyl)-Valyl-n-(2,3-Dihydro-1H-Inden-2-Yl)Glycine n-(3-(1,1,1-Trifluoro-4-Methyl-2-Oxopentyl))Amide is a sophisticated, high-purity synthetic organic compound designed for advanced research and development. Its complex molecular architecture, featuring valine, glycine, and trifluoromethyl ketone pharmacophores, makes it a critical intermediate for probing specific biochemical pathways. This compound is essential for pharmaceutical and biotechnology organizations focused on innovative drug discovery, particularly in areas requiring targeted enzyme inhibition or receptor modulation.

Application

This specialized chemical serves as a key building block in several high-value research and development applications:

• Pharmaceutical Research Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific disease mechanisms.
• Protease Inhibitor Development: Used in the design and study of inhibitors for proteolytic enzymes, given its peptide-like backbone and functional groups.
• Biochemical Probe Synthesis: Employed to create molecular tools for studying enzyme function, protein-protein interactions, and cellular signaling pathways.
• Medicinal Chemistry & Lead Optimization: Provides a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of drug candidates.
• Academic and Institutional Research: Supports fundamental chemical and biological research in universities and government laboratories.
• Contract Research Organization (CRO) Projects: Supplied to CROs conducting custom synthesis and bioassay services for client-driven discovery programs.

Basic Information

Item	Details
Product Name	n-((4-((((4-Chlorophenyl)Sulfonyl)Amino)Carbonyl)Phenyl)Oxomethyl)-Valyl-n-(2,3-Dihydro-1H-Inden-2-Yl)Glycine n-(3-(1,1,1-Trifluoro-4-Methyl-2-Oxopentyl))Amide
CAS No.	129585-37-1
Molecular Formula	C34H33ClF3N3O7S
Molecular Weight	720.15 g/mol
Synonyms	Valyl-glycine derivative trifluoromethyl ketone amide; 129585-37-1; N-[(4-{[(4-Chlorophenyl)sulfonyl]carbamoyl}phenyl)carbonyl]-L-valyl-N-(2,3-dihydro-1H-inden-2-yl)glycyl-3,3,3-trifluoro-2-(2-methylpropyl)-2-oxopropylamine; L-Valyl-N-(2,3-dihydro-1H-inden-2-yl)glycyl-3,3,3-trifluoro-2-(2-methylpropyl)-2-oxopropylamide 4-{[(4-Chlorophenyl)sulfonyl]carbamoyl}benzoic acid derivative; Protease inhibitor intermediate; Peptidomimetic trifluoroketone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and purified to meet exacting R&D standards, with identity and purity confirmed by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical data is provided with each shipment to ensure full traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.