Description

Prostaglandin E2 Azidophenacyl Ester is a chemically modified derivative of Prostaglandin E2 (PGE2), designed as a versatile biochemical tool for advanced research applications. This compound is engineered to facilitate the study of prostaglandin signaling pathways through photoaffinity labeling and cross-linking techniques. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on inflammation, immunology, and reproductive biology.

Application

• Photoaffinity Labeling: Acts as a critical probe for identifying and characterizing prostaglandin receptors and binding proteins in complex biological systems.
• Biochemical Cross-linking: Used to study protein-protein interactions and map the architecture of signaling complexes involving the PGE2 pathway.
• Prostaglandin Receptor Research: Serves as a key reagent for investigating the structure, function, and localization of EP receptor subtypes.
• Drug Discovery Platforms: Employed in high-throughput screening assays and target validation studies for novel anti-inflammatory and analgesic therapeutics.
• Mechanistic Studies: Enables detailed exploration of PGE2-mediated processes in cellular models of pain, fever, and inflammation.
• Probe Development: Used as a precursor for synthesizing fluorescent or biotinylated conjugates for advanced detection and imaging applications.

Basic Information

Product Name	Prostaglandin E2 Azidophenacyl Ester
CAS No.	129163-95-7
Molecular Formula	C29H37N3O6
Molecular Weight	523.62 g/mol
Synonyms	PGE2 Azidophenacyl Ester; 11α,15α-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid 2-(4-Azidophenacyl) Ester; 9-Oxo-11α,15α-dihydroxyprosta-5,13-dien-1-oic Acid 2-(4-Azidophenacyl) Ester; Azidophenacyl PGE2; PGE2-APE; Photoactivatable PGE2 Analog; Prostaglandin E2 2-(4-Azidobenzoyl)ethyl Ester
EINECS	Contact for details

Quality Control

Our Prostaglandin E2 Azidophenacyl Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability data. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the rigorous demands of pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.