Description

L-Tyrosine-β-13C is a stable isotope-labeled analog of the essential amino acid L-Tyrosine, specifically enriched with carbon-13 at the beta position. This high-purity labeled compound is critical for advanced research requiring precise metabolic and pharmacokinetic tracing. It is primarily utilized by pharmaceutical R&D, academic research institutions, and analytical laboratories engaged in mass spectrometry, NMR spectroscopy, and metabolic pathway studies.

Application

• Isotope-Labeled Internal Standard for accurate quantification in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Metabolic Flux Analysis (MFA) and tracer studies to investigate tyrosine metabolism, protein synthesis, and neurotransmitter (dopamine, epinephrine) biosynthesis pathways.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Research for drug development, enabling precise tracking of drug metabolites and biochemical precursors.
• Nuclear Magnetic Resonance (NMR) Spectroscopy as a probe for studying protein structure, dynamics, and molecular interactions.
• Biomedical Research into disorders related to tyrosine metabolism, such as tyrosinemia and Parkinson's disease.
• Nutritional Science Studies examining amino acid absorption, utilization, and turnover in vivo.

Basic Information

Product Name	L-Tyrosine-β-13C
CAS No.	129077-96-9
Molecular Formula	C813CH11NO3 *
Molecular Weight	182.18 g/mol (for 13C1 labeled form)
Synonyms	(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid-β-13C; L-Tyrosine-3-13C; L-Tyrosine (β-13C); L-Tyrosine (3-13C); (2S)-2-Amino-3-(4-hydroxyphenyl)propanoic-3-13C acid; Tyrosine-β-13C; 13C Labeled L-Tyrosine; L-Tyrosine (13C labeled)
EINECS	Contact for details

* Formula indicates 13C labeling at the beta (3-) carbon position of the propanoic acid side chain.

Quality Control

Our L-Tyrosine-β-13C is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 13C), chemical purity by HPLC, and confirmation of stereochemical integrity. We adhere to cGMP principles for research chemicals, and specifications can be tailored to meet the rigorous standards of USP and Pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Confirms 13C labeling at β-position
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Optical Rotation	[α]D20: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.