Description

Isovaleryl-Valyl-Valyl-Leucine Phosphinate-3-Phenyllactic Acid Methyl Ester is a specialized synthetic peptide derivative designed for advanced research and development applications. This compound is valued for its role as a key intermediate or building block in the synthesis of novel bioactive molecules, particularly in the field of protease inhibitor research. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on medicinal chemistry and drug discovery programs targeting specific enzymatic pathways.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel protease inhibitors and other therapeutic peptide analogs.
• Medicinal Chemistry: Used as a building block for structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Biochemical Research: Employed in enzymatic studies as a potential substrate or inhibitor to investigate specific protease mechanisms.
• Preclinical Development: Acts as a key starting material for scaling up the production of candidate compounds for further biological evaluation.
• Chemical Biology: Utilized in the design and development of activity-based probes for studying enzyme function in complex biological systems.

Basic Information

Product Name	Isovaleryl-Valyl-Valyl-Leucine Phosphinate-3-Phenyllactic Acid Methyl Ester
CAS No.	128923-36-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Isovaleryl-Val-Val-Leu(P)(O)-Phe-Lac-OMe; IVV-Leu(P)-Phe-Lac-OMe; Peptidyl Phosphonate Ester; Protease Inhibitor Intermediate; N-Isovaleryl-L-valyl-L-valyl-L-leucylphosphinyl-(3-phenyl-D-lactate) methyl ester; CAS 128923-36-4; (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(3-Methylbutanoyl)amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentyl]hydroxyphosphinyl]oxy-3-phenylpropanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Isovaleryl-Valyl-Valyl-Leucine Phosphinate-3-Phenyllactic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are accompanied by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.