Description

Benzyloxycarbonylalanyl-Alanyl-Leucyl Phosphinate-3-Phenyllactic Acid Methyl Ester is a specialized synthetic peptide derivative designed as a potent and selective protease inhibitor. This compound is critical for biochemical research and pharmaceutical development, particularly in the study of enzyme mechanisms and the design of therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on developing novel treatments for conditions involving proteolytic dysregulation.

Application

• Protease Inhibition Research: Serves as a key biochemical tool for studying the activity and inhibition mechanisms of specific proteases, including serine and cysteine proteases.
• Drug Discovery & Development: Used as a lead compound or intermediate in the design and synthesis of novel therapeutic agents targeting pathological enzyme activity.
• Biochemical Assay Development: Employed as a standard or reference inhibitor in high-throughput screening (HTS) assays to identify new drug candidates.
• Academic Research: Facilitates fundamental studies in enzymology, structural biology, and medicinal chemistry within university and institutional laboratories.
• Peptide Chemistry Studies: Acts as a model compound for investigating peptide-phosphinate interactions and stability, advancing synthetic methodology.

Basic Information

Product Name	Benzyloxycarbonylalanyl-Alanyl-Leucyl Phosphinate-3-Phenyllactic Acid Methyl Ester
CAS No.	128901-55-3
Molecular Formula	C31H42N4O9P
Molecular Weight	645.66 g/mol
Synonyms	Z-Ala-Ala-Leu(P)-(O)-Phe-OMe; Z-Ala-Ala-Leu(P)-(O)-Phe-OMe; Cbz-Ala-Ala-Leu(P)-(O)-Phe-OMe; Benzyloxycarbonyl-Ala-Ala-Leu(P)-(O)-Phe-OMe; Ala-Ala-Leu Phosphinate Derivative; Protease Inhibitor 128901-55-3; Peptidyl Phosphonate Ester; Z-AAL(Phe)OMe
EINECS	Contact for details

Quality Control

Our Benzyloxycarbonylalanyl-Alanyl-Leucyl Phosphinate-3-Phenyllactic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.