Description

Benzo[B]Thiophene-2-Sulfonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci) is a specialized heterocyclic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive sulfonyl chloride group, which enables the efficient introduction of the tetrahydrobenzo[b]thiophene sulfonamide moiety into target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, enzyme inhibition, or receptor modulation.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfonamide group can enhance biological activity and selectivity.
• Material Science Research: Employed in the creation of specialty polymers, ligands for catalysis, or organic electronic materials due to its unique fused-ring structure.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or other biomolecules to study biological pathways and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	Benzo[B]Thiophene-2-Sulfonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci)
CAS No.	128852-17-5
Molecular Formula	C8H9ClO2S2
Molecular Weight	236.74 g/mol
Synonyms	4,5,6,7-Tetrahydro-1-benzothiophene-2-sulfonyl chloride; 4,5,6,7-Tetrahydrobenzo[b]thiophene-2-sulfonyl chloride; 2-Thiophenesulfonyl chloride, 4,5,6,7-tetrahydrobenzo-; Tetrahydrobenzo[b]thiophene-2-sulfonyl chloride; 4,5,6,7-Tetrahydro-2-benzothiophenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Benzo[B]Thiophene-2-Sulfonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.