Description

Pnu-282987 S Enantiomer Hydrochloride is a high-purity, single-enantiomer compound of significant interest in advanced pharmaceutical research and development. This specificity matters because the S-enantiomer often exhibits distinct and potent biological activity compared to its R-counterpart, making it a critical intermediate for developing selective therapeutics. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the fields of neuroscience and receptor-targeted drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Neuroscience Research: Used as a reference standard or active compound in studies related to neurological receptors and signal transduction.
• Preclinical Development: Employed in the formulation and testing of new chemical entities during early-stage drug development.
• Biochemical Assays: Utilized as a ligand or inhibitor in high-throughput screening and in vitro assay systems to study receptor-ligand interactions.
• Metabolite Synthesis: Acts as a precursor for the synthesis of potential drug metabolites for identification and safety testing.
• Academic Research: Provides a pure enantiomeric standard for universities and research labs focusing on stereochemistry and medicinal chemistry.

Basic Information

Product Name	Pnu-282987 S Enantiomer Hydrochloride
CAS No.	128311-08-0
Molecular Formula	C17H21N3O2 • HCl
Molecular Weight	335.83 g/mol (as hydrochloride salt)
Synonyms	PNU-282987 (S-enantiomer) hydrochloride; (S)-N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide hydrochloride; S-PNU-282987 HCl; (S)-PNU 282987 hydrochloride; PNU282987 (S) HCl; 5-[(3R)-3-[(5S)-3,4-Dihydro-5H-pyrido[3,2-b][1,4]diazepin-5-yl]-1-piperidinyl]-2(1H)-quinolinone hydrochloride (related structure); S-Enantiomer of PNU-282987 hydrochloride
EINECS	Contact for details

Quality Control

Our Pnu-282987 S Enantiomer Hydrochloride is manufactured under controlled conditions to ensure high enantiomeric purity and chemical integrity. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification and NMR for structural confirmation, to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.