Description

5-(4-Fluorophenyl)Oxazole is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring an oxazole ring linked to a fluorinated phenyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a foundational component in the creation of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl-oxazole scaffold.
• Material Science Research: Used in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials, due to its electron-transporting capabilities.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Fluorescent Probe Synthesis: Employed in the design and synthesis of fluorescent dyes and molecular probes for bioimaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for building compound libraries in high-throughput screening.

Basic Information

Product Name	5-(4-Fluorophenyl)Oxazole
CAS No.	128101-19-9
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	5-(4-Fluorophenyl)-1,3-oxazole; 4-(1,3-Oxazol-5-yl)fluorobenzene; 5-(p-Fluorophenyl)oxazole; 5-(4-Fluorophenyl)-oxazole; Oxazole, 5-(4-fluorophenyl)-; Fluorophenyloxazole
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)Oxazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.