Description

4-Bromo-2-Fluoropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an invaluable intermediate for introducing functional complexity into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	4-Bromo-2-Fluoropyridine
CAS No.	128071-98-7
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	2-Fluoro-4-bromopyridine; 4-Bromo-2-fluoropyridine; 2-Fluoro-4-bromo-pyridine; Pyridine, 4-bromo-2-fluoro-; 4-Bromo-2-fluoro-pyridine; 128071-98-7; 4-Br-2-F-Py
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.