Description

4-Bromo-2-Fluoropyridine-3-Carboxaldehyde is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents adjacent to an aldehyde group, makes it an indispensable precursor for constructing complex heterocyclic frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials, liquid crystals, and organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	4-Bromo-2-Fluoropyridine-3-Carboxaldehyde
CAS No.	128071-77-2
Molecular Formula	C6H3BrFNO
Molecular Weight	204.00 g/mol
Synonyms	3-Formyl-4-bromo-2-fluoropyridine; 2-Fluoro-4-bromopyridine-3-carboxaldehyde; 4-Bromo-2-fluoro-3-pyridinecarboxaldehyde; 4-Bromo-2-fluoronicotinaldehyde; 128071-77-2; 4-Bromo-2-fluoropyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoropyridine-3-Carboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its properties, it is recommended to store this material under an inert atmosphere to prevent oxidation and in a moisture-controlled environment. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.