Description

Homomannojirimycin is a potent and specific glycosidase inhibitor derived from the mannojirimycin family. This compound is a critical research tool and building block in medicinal chemistry, valued for its ability to selectively modulate carbohydrate-processing enzymes. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery, enzyme mechanism studies, and the synthesis of novel therapeutic agents targeting metabolic and infectious diseases.

Application

• Glycosidase Inhibition Studies: A key biochemical tool for investigating the mechanism and kinetics of α-mannosidase and related enzymes.
• Antiviral Research: Investigated for its potential to interfere with viral glycoprotein processing, offering a pathway for novel antiviral drug development.
• Metabolic Disorder Research: Used in studies related to lysosomal storage diseases and diabetes where glycosidase activity is a therapeutic target.
• Medicinal Chemistry Synthesis: Serves as a sophisticated chiral precursor or scaffold for the synthesis of more complex glycomimetics and pharmaceutical candidates.
• Cell Biology & Glycobiology: Employed to perturb N-linked glycan processing in cell cultures, helping to elucidate glycoprotein function and trafficking.
• Quality Control Standard: Used as a reference standard in analytical laboratories for method development and validation in pharmaceutical quality control.

Basic Information

Product Name	Homomannojirimycin
CAS No.	127995-29-3
Molecular Formula	C7H15NO4
Molecular Weight	177.20 g/mol
Synonyms	1,5-Dideoxy-1,5-imino-D-mannitol; D-Homomannojirimycin; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol; 1-Deoxymannojirimycin homologue; Isofagomine precursor
EINECS	Contact for details

Quality Control

Our Homomannojirimycin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.