Description

2-(Acetylamino)-2-Deoxy-D-Glucose Labeled With Carbon-13 is a stable isotope-labeled derivative of N-acetylglucosamine, a fundamental building block in glycobiology. This compound matters as a critical internal standard and tracer for advanced metabolic and biochemical research, enabling precise quantification and pathway analysis. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and diagnostic developers working in areas such as carbohydrate metabolism, glycosylation studies, and biomarker discovery.

Application

• Metabolic Pathway Tracing: Used as a Carbon-13 labeled tracer in NMR and mass spectrometry studies to elucidate biosynthetic pathways of glycans and glycosaminoglycans.
• Quantitative Mass Spectrometry: Serves as a stable isotope-labeled internal standard (SIL-IS) for the accurate LC-MS/MS quantification of N-acetylglucosamine and related metabolites in complex biological matrices.
• Glycobiology Research: Essential for studying enzymatic activities of glycosyltransferases and glycosidases, and for probing the structure and function of glycoproteins.
• Pharmaceutical Development: Applied in drug discovery programs targeting metabolic disorders, inflammation, and cancer where hexosamine biosynthesis pathway (HBP) flux is a key parameter.
• Diagnostic Assay Development: Utilized in the development of clinical assays for monitoring specific carbohydrate metabolites associated with disease states.

Basic Information

Item	Details
Product Name	2-(Acetylamino)-2-Deoxy-D-Glucose Labeled With Carbon-13
CAS No.	127959-06-2
Molecular Formula	C8H15NO6 (with 13C labeling)
Molecular Weight	~222.2 g/mol (exact mass depends on labeling position)
Synonyms	N-Acetyl-D-glucosamine-13C; N-Acetyl-13C-glucosamine; GlcNAc-13C; 2-Acetamido-2-deoxy-D-glucose-13C; 2-(Acetylamino)-2-deoxy-D-glucopyranose-13C; NAG-13C; (3R,4R,5S,6R)-5-acetamido-6-(hydroxymethyl)oxane-2,3,4-triol-13C
EINECS	Contact for details

Quality Control

Every batch of our Carbon-13 labeled N-acetylglucosamine is produced and tested under a strict quality management system. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR and HPLC-MS. Certificates of Analysis (COA) are provided with each shipment, detailing assay, isotopic enrichment, and impurity profiles to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C (at designated position)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.