Description

(S)-1-[2-(Trifluoromethyl)Phenyl]Ethanol is a high-value chiral intermediate characterized by its phenyl ethanol core substituted with a trifluoromethyl group at the ortho position. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where its specific stereochemistry and fluorine substitution impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Key chiral intermediate in the synthesis of pharmaceutical active ingredients, particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Building block for advanced agrochemicals, leveraging the trifluoromethyl group to enhance biological activity and environmental persistence.
• Precursor in the development of liquid crystal materials and other advanced organic electronic components.
• Starting material for asymmetric synthesis and catalysis research in academic and industrial laboratories.
• Intermediate for producing specialty fine chemicals and flavors & fragrances requiring specific stereochemistry.
• Used in methodological studies for developing new fluorination and chiral resolution techniques.

Basic Information

Product Name	(S)-1-[2-(Trifluoromethyl)Phenyl]Ethanol
CAS No.	127852-27-1
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	(S)-1-(2-Trifluoromethylphenyl)ethanol; (S)-α-(Trifluoromethyl)benzyl alcohol; (S)-2-(Trifluoromethyl)phenethyl alcohol; (S)-1-[2-(Trifluoromethyl)phenyl]ethan-1-ol; (S)-o-(Trifluoromethyl)phenethyl alcohol; (S)-(-)-1-(2-Trifluoromethylphenyl)ethanol; (S)-1-(α,α,α-Trifluoro-o-tolyl)ethanol
EINECS	Contact for details

Quality Control

Our (S)-1-[2-(Trifluoromethyl)Phenyl]Ethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.