Description

1-(2-Fluorophenyl)-2-Methylpropan-2-Ol is a specialized fluorinated tertiary alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a fluorinated aromatic ring and a hindered alcohol group, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis, leveraging the steric bulk of the tertiary alcohol group.
• Material Science Research: Employed in the synthesis of specialty monomers or additives for advanced polymers, where fluorination can impart unique surface properties and chemical resistance.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of natural products or biochemical probes to study enzyme mechanisms and binding interactions.

Basic Information

Product Name	1-(2-Fluorophenyl)-2-Methylpropan-2-Ol
CAS No.	1960-55-0
Molecular Formula	C10H13FO
Molecular Weight	168.21 g/mol
Synonyms	2-(2-Fluorophenyl)-2-propanol; 1-(2-Fluorophenyl)-2-methyl-2-propanol; α,α-Dimethyl-2-fluorobenzyl alcohol; 2-Fluoro-α,α-dimethylbenzyl alcohol; (2-Fluorophenyl)dimethylcarbinol; 2-(2-Fluorophenyl)isopropanol; 2-Fluoro-α-methyl-α-phenylmethanol (related); Tertiary alcohol 1960-55-0
EINECS	217-815-3

Quality Control

Our production of 1-(2-Fluorophenyl)-2-Methylpropan-2-Ol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.