Description

3-Pentafluorophenyl-Propan-1-Ol is a versatile fluorinated organic building block characterized by a propanol chain attached to a perfluorinated phenyl ring. This unique structure makes it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where the introduction of fluorine atoms can dramatically alter properties like metabolic stability, lipophilicity, and bioavailability. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate pentafluorophenyl motifs into their molecular designs.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving thermal stability and optical properties.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing chemical resistance, reducing surface energy, and improving material performance.
• Cross-coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Ligand & Catalyst Development: Useful for synthesizing specialized fluorinated ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	3-Pentafluorophenyl-Propan-1-Ol
CAS No.	1988-55-2
Molecular Formula	C9H7F5O
Molecular Weight	226.15 g/mol
Synonyms	3-(Pentafluorophenyl)-1-propanol; 3-(Pentafluorophenyl)propan-1-ol; 1-Propanol, 3-(pentafluorophenyl)-; 3-Pentafluorophenylpropanol; Pentafluorophenylpropyl alcohol; 3-(Perfluorophenyl)propan-1-ol; 3-(C6F5)CH2CH2CH2OH
EINECS	217-875-6

Quality Control

Our 3-Pentafluorophenyl-Propan-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent oxidation or degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.