Description

(2-Chloro-3-Fluoro-5-Nitro-Phenyl)-Methanol is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique halogenated nitrobenzene alcohol structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a versatile building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Material Research: Used in the development of advanced electronic materials, including components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized azo dyes and high-performance pigments requiring halogen and nitro functional groups.
• Cross-Coupling Reactions: Valuable substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Polymer Modification: Functional monomer for introducing specific aromatic and polar groups into polymer backbones to alter material properties.

Basic Information

Product Name	(2-Chloro-3-Fluoro-5-Nitro-Phenyl)-Methanol
CAS No.	101336-15-6
Molecular Formula	C7H5ClFNO3
Molecular Weight	205.57 g/mol
Synonyms	2-Chloro-3-fluoro-5-nitrobenzenemethanol; (2-Chloro-3-fluoro-5-nitrophenyl)methanol; 1-(Chloro)-2-fluoro-4-(hydroxymethyl)-6-nitrobenzene; 2-Chloro-3-fluoro-5-nitrobenzyl alcohol; Benzenemethanol, 2-chloro-3-fluoro-5-nitro-; 3-Fluoro-2-chloro-5-nitrobenzyl alcohol
EINECS	Contact for details

Quality Control

Our (2-Chloro-3-Fluoro-5-Nitro-Phenyl)-Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.