Description

4,4,4-Trifluoro-2-Butanol is a fluorinated alcohol building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl group, enabling the synthesis of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate fluorine for enhanced bioactivity, stability, or surface characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine moiety improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated into specialty polymers and coatings to enhance chemical resistance, reduce surface energy, and improve weatherability.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and coupling reactions to introduce the -CH(OH)CF3 moiety into complex molecular architectures.
• Surface Active Agents: Used in the formulation of specialty surfactants and fluorosurfactants for demanding industrial applications.

Basic Information

Product Name	4,4,4-Trifluoro-2-Butanol
CAS No.	101054-93-7
Molecular Formula	C4H7F3O
Molecular Weight	128.09 g/mol
Synonyms	2-Butanol, 4,4,4-trifluoro-; 4,4,4-Trifluorobutan-2-ol; 1,1,1-Trifluoro-3-hydroxybutane; 3-Hydroxy-1,1,1-trifluorobutane; TFBA; Trifluorobutanol
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-2-Butanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The product is moisture-sensitive; keep container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.