Description

2-(4-Amino-3-Chloro-Phenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol is a high-value fluorinated aromatic intermediate featuring a unique combination of an amino group, a chloro substituent, and a hexafluoroisopropanol moiety. This compound is critical for its role in synthesizing advanced materials and active pharmaceutical ingredients (APIs) where the introduction of fluorine atoms is required to modulate biological activity, stability, and physicochemical properties. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymers, enhancing their chemical resistance, thermal properties, and surface characteristics.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D for exploring new fluorination reactions and creating complex molecular architectures.
• Advanced Material Development: Used in the creation of specialty coatings and electronic materials that require specific optical or electronic properties.

Basic Information

Product Name	2-(4-Amino-3-Chloro-Phenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol
CAS No.	1992-30-9
Molecular Formula	C9H6ClF6NO
Molecular Weight	293.59 g/mol
Synonyms	3-Chloro-4-(1,1,1,3,3,3-Hexafluoro-2-Hydroxypropan-2-yl)Aniline; 4-Amino-3-Chloro-α,α-Bis(trifluoromethyl)Benzenemethanol; 2-(4-Amino-3-Chlorophenyl)Hexafluoroisopropanol; 2-(4-Amino-3-Chloro-Phenyl)-1,1,1,3,3,3-Hexafluoro-2-Propanol; 4-(1,1,1,3,3,3-Hexafluoro-2-Hydroxy-2-Propyl)-2-Chloroaniline; 2-(4-Amino-3-Chlorophenyl)-1,1,1,3,3,3-Hexafluoropropan-2-ol; 3-Chloro-4-(hexafluoro-2-hydroxyisopropyl)aniline
EINECS	Contact for details

Quality Control

Our 2-(4-Amino-3-Chloro-Phenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent composition suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.